Publications by authors named "S Liyanage"

Hypertension (HTN) is recognized as a major modifiable risk factor for cardiovascular deaths in South Asia. Our aim was to furnish a comprehensive analysis of HTN prevalence, trends, control efforts, awareness, barriers in care delivery and associated factors, based on nationally derived evidence in Sri Lanka. A systematic search of online databases (PubMed, Web of Science, Scopus), local journals and repositories yielded 6704 results, of which 106 were included.

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Introduction: Hypertension is the leading preventable cause of cardiovascular morbidity and mortality globally, with a disproportionate impact on low-income and middle-income countries like Sri Lanka. Effective blood pressure (BP) control improves outcomes in patients with hypertension. This study aimed to assess the prevalence of uncontrolled hypertension, and its correlates among Sri Lankan patients with hypertension in clinic settings.

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Objectives: This study investigates the potential health risks associated with exposure to extremely low-frequency magnetic fields (ELF-MFs), focusing on the impact on sleep quality. The hypothesis is that increasing ELF-MF exposure will correlate with elevated blood pressure (BP), altered heart rate (HR) dynamics and poorer sleep quality among occupational workers in Korea.

Methods: The study involved 85 participants.

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Article Synopsis
  • Pharmacogenomics is gaining traction in South Asia, particularly in Sri Lanka, aiming to enhance drug therapies and minimize side effects for patients.
  • A comprehensive review analyzed research in Sri Lanka, where studies were classified into categories like clinical correlational, descriptive, and novel assay development; 11 articles and 8 theses were reviewed.
  • While progress has been made, additional clinical studies and a wider scope of genomic research are necessary, alongside efforts to address challenges like funding and public awareness, to successfully implement personalized medicine in the region.
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Reconstituted high-density lipoproteins (rHDL) improve wound healing in diabetes. We aimed to determine if rHDL elicit anti-inflammatory effects in diabetic wounds, as a mechanism to explain their wound healing benefits. Diabetes was induced using streptozotocin in C57Bl6/J mice.

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