Brain Health Attitudes, Awareness and Actions in Middle-Aged Latinos.

Alzheimer's disease and related dementias (ADRD) disproportionately impact Latinos in the US. Interventions that promote engagement in established protective behaviors throughout the life course may offer an opportunity to address disparities. To inform brain health promotion efforts, this study aimed to examine current brain health-related attitudes, awareness, and actions of middle-aged Latinos.

Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates.

Astrocytes are a highly abundant glial cell type and perform critical homeostatic functions in the central nervous system. Like neurons, astrocytes have many discrete heterogeneous subtypes. The subtype identity and functions are, at least in part, associated with their anatomical location and can be highly restricted to strategically important anatomical domains.

Ribosomal protein phylogeography offers quantitative insights into the efficacy of genome-resolved surveys of microbial communities.

The increasing availability of microbial genomes is essential to gain insights into microbial ecology and evolution that can propel biotechnological and biomedical advances. Recent advances in genome recovery have significantly expanded the catalogue of microbial genomes from diverse habitats. However, the ability to explain how well a set of genomes account for the diversity in a given environment remains challenging for individual studies or biome-specific databases.

Gut Bacteria Metabolize Natural and Synthetic Steroid Hormones via the Reductive OsrABC Pathway.

Steroid hormone metabolism by the gut microbiome has multiple implications for mammalian physiology, but the underlying mechanisms and broader significance of this activity remains largely unknown. Here, we isolate a novel human gut bacterium, strain HCS.1, that reduces cortisol, progesterone, testosterone, and related steroid hormones to 3β,5β-tetrahydrosteroid products.

Perceptions of brain health and aging among middle-aged latinos: A qualitative paper.

Objectives: Latinos living in the US are disproportionately impacted by Alzheimer's disease and related dementias (ADRD). To develop culturally-informed interventions, a first step is engaging with key stakeholders. The present study aimed to explore perspectives on brain health and aging among middle-aged Latinos living in Chicago, IL.