Publications by authors named "S Lekuthai"

Article Synopsis
  • - This study used bioinformatics and phenotypic tests to analyze the features of a carbapenem-resistant bacteria strain, AB073, which showed resistance to seven different classes of antibiotics due to various mechanisms like altered targets and efflux.
  • - AB073 could not transfer its antibiotic resistance through conjugation, and genetic analysis found no links to horizontal gene transfer, indicating that its resistance traits are likely innate rather than acquired.
  • - The strain also possesses genes related to virulence factors, iron uptake, and biofilm formation, highlighting its successful spread as a pathogen in various regions and clinical settings, particularly originating from Thailand.
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Our study suggests that the administration of bronchodilator drug via nebulizer powered by flow rate 6 L/min is more suitable in COPD patients. The oxygen flow rates should not be given more than 6 L/min. In this study, we recruited COPD patients in a stable stage, in whom the risk of hyperoxic induced hypercarbia is less than in the acute exacerbation stage.

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