Effect of brief intense stair climbing on cardiorespiratory fitness and metabolic risk factors in inactive young men with obesity: A randomized controlled trial.

Background And Aim: We investigated the effects of brief, intense stair climbing on cardiorespiratory fitness (CRF) and cardiometabolic risk factors in young Korean men with obesity.

Methods And Results: Twenty-four healthy men (age: 25.8 ± 2.

Different Mortality and Transfer Rates Between Teaching and Nonteaching Urban Hospitals Among Patients Presenting with Stevens-Johnson Syndrome.

Stevens-Johnson Syndrome is a rare disorder of the skin and mucous membranes accompanied by systemic symptoms that are life threatening and require immediate intervention. We sought to determine if different hospital types, specifically urban nonteaching hospitals versus urban teaching hospitals, have different outcomes among patients presenting with Stevens-Johnson Syndrome during hospitalization. Patients presenting to urban teaching and urban nonteaching hospitals were compared.

Delphi consensus-based recommendations of tools and outcomes for the assessment of radiation dermatitis severity.

Introduction: Acute radiation dermatitis (ARD) is a common side effect experienced during radiation therapy (RT) for cancer. Published clinical trials for ARD use a myriad of assessment tools and outcomes to measure ARD severity, which limits the comparability of clinical trial results. Our study utilized a modified Delphi consensus survey to gather expert opinions on commonly used tools for ARD severity.

A phase 1b study of cofetuzumab pelidotin monotherapy in patients with PTK7-expressing recurrent non-small cell lung cancer.

Background: Protein tyrosine kinase 7 (PTK7) overexpression in lung cancer is associated with tumor progression. Cofetuzumab pelidotin (Cofe-P) is an antibody-drug conjugate comprising an anti-PTK7 antibody conjugated to a microtubule inhibitor. Herein, we report the results of a phase 1b study evaluating Cofe-P safety, efficacy, and pharmacokinetics in patients with recurrent non-small cell lung cancer (NSCLC).

Improved Limit on Neutrinoless Double Beta Decay of ^{100}Mo from AMoRE-I.

AMoRE searches for the neutrinoless double beta decay using 100 kg of enriched ^{100}Mo. Scintillating molybdate crystals coupled with a metallic magnetic calorimeter operate at milli-Kelvin temperatures to measure the energy of electrons emitted in the decay. AMoRE-I is a demonstrator for the full-scale AMoRE, operated at the Yangyang Underground Laboratory for over two years.