Publications by authors named "S Le Lay"
Objective: To investigate the positioning of deep epigastric vessels in obese patients to determine the need to redefine laparoscopic port placement 'safe zones' based on body habitus.
Design: Retrospective case series.
Setting: University-affiliated 500-bed hospital.
Article Synopsis
- The ovarian follicle's development relies on factors from both the blood and follicular cells, with extracellular vesicles (EVs) playing a crucial role in communication within the follicle.
- Recent findings indicate that EVs are involved in follicular development and disorders like polycystic ovary syndrome (PCOS), with different protein patterns seen in EVs from follicular fluid (FF) and plasma.
- sEVs from normal patients enhance steroid hormone secretion in granulosa cells, while those from PCOS patients fail to do so, indicating that PCOS alters granulosa cell functions, including inflammation and steroid production.
Article Synopsis
- * Researchers developed a T cell vaccine targeting key ZIKV T cell epitopes, testing its effectiveness in mice, using a DNA vaccine platform.
- * The vaccine showed strong protection against ZIKV while demonstrating limited effectiveness against DENV2; however, a separate DENV1-based vaccine effectively protected against both DENV1 and DENV2, highlighting the potential of T-cell vaccination to tackle multiple flavivirus infections.
Article Synopsis
- The study aimed to identify the optimal sizes for middle cerebral artery (MCA) bifurcation aneurysms that are most suitable for treatment with the Woven EndoBridge (WEB) device, focusing on aneurysm width and neck dimensions.
- Using a large retrospective database, the researchers analyzed unruptured MCA bifurcation aneurysms and established ideal cutoff values of 6.1 mm for width and 4.6 mm for neck size regarding treatment effectiveness.
- Findings indicated that aneurysms smaller than these cutoff values had significantly higher rates of occlusion (93% for width and 90% for neck) and lower retreatment rates compared to larger aneurysms, highlighting the importance of