Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey.

Background: Chronic cough (persisting for ≥8 weeks) is a common disorder affecting approximately 5 to 10% of adults worldwide that is sometimes refractory to treatment (refractory chronic cough [RCC]) or has no identifiable cause (unexplained chronic cough [UCC]). There is minimal information on the patient's experience of RCC/UCC in Canada. The aim of this study was to evaluate the patient journey and perceptions related to RCC/UCC management in Canada.

Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey.

Introduction: Chronic cough (persisting for ≥ 8 weeks) is a common disorder that includes refractory chronic cough (RCC; cough that persists despite treatment of underlying disease) and unexplained chronic cough (UCC; cough with no identifiable cause). We evaluated self-reported health-related quality of life (HR-QoL) and work/activity impairment associated with RCC/UCC in Canada.

Methods: Our exploratory study included Canadians in the Leger Opinion Panel with RCC or UCC.

Development of a Dualistic Model of Sexual Passion: Investigating Determinants and Consequences.

In empirical research, sexual passion has frequently been conceptualized as the interdependent dynamics experienced with a partner and as following a unidimensional continuum of intensity. A recent theoretical model conceptualized sexual passion as an intrapersonal motivation, which can energize both partnered and non-partnered sexual behaviors (Philippe, Vallerand, Bernard-Desrosiers, Guilbault, & Rajotte, 2017). This model also departs from the typical unidimensional continuum by positing the existence of two types of sexual passion: harmonious sexual passion (HSP) and obsessive sexual passion (OSP).

Validating the theoretical bases of sleep reactivation during sharp-wave ripples and their association with emotional valence.

Sleep is important for memory consolidation, and an abundant literature suggests that reactivation in the hippocampus during sleep is instrumental to this process. Yet, the current interpretation of activity during sharp-waves ripples (SWRs), as replay of wake experiences, relies on hypotheses that, while widely accepted, have only recently begun to be tested directly. Moreover, this theory has been mainly studied in the context of pure spatial learning, and it is still not clear how emotional valence can fit into this conceptual framework when considering reward- or punishment-based learning.

Beyond spindles: interactions between sleep spindles and boundary frequencies during cued reactivation of motor memory representations.

There is now ample evidence that sleep spindles play a critical role in the consolidation of newly acquired motor sequences. Previous studies have also revealed that the interplay between different types of sleep oscillations (e.g.