Cranioencephalic functional lymphoid units in glioblastoma.

The ecosystem of brain tumors is considered immunosuppressed, but our current knowledge may be incomplete. Here we analyzed clinical cell and tissue specimens derived from patients presenting with glioblastoma or nonmalignant intracranial disease to report that the cranial bone (CB) marrow, in juxtaposition to treatment-naive glioblastoma tumors, harbors active lymphoid populations at the time of initial diagnosis. Clinical and anatomical imaging, single-cell molecular and immune cell profiling and quantification of tumor reactivity identified CD8 T cell clonotypes in the CB that were also found in the tumor.

A rare case report: Primary isolated hydatid cyst of the spleen- diagnosis and management.

Introduction And Importance: Hydatid disease is widespread in agricultural regions and globally. Tunisia is notably affected in the Mediterranean. Although liver involvement is common, splenic hydatidosis is rare, with incidence worldwide ranging from 0.

Reversed midgut rotation revealed by cecal volvulus in the elderly: A case report.

Introduction: Reverse midgut rotation constituted an extremely rare intestinal malrotation. Its recognition in the elderly was challenging as in our case revealed by cecal volvulus.

Case Presentation: A 78-years old man consulted for diffuse abdominal, vomiting, bowel movement and passing gas inability.

Arteriovenous gastric malformation: A challenging diagnosis. A case report.

Introduction: Gastro-intestinal bleeding etiological diagnosis could be challenging especially for rare etiologies as it was the case of our patient having an arteriovenous gastric malformation.

Case Presentation: A 50-years old man consulted for hematemesis. Esophagogastroduodenoscopy didn't show bleeding signs.

Exceptional vascular variants during oncological right colectomy: Case reports.

Introduction: Carcinological right colectomy with complete D3 mesocolon excision has to be guided by vascular variants in order to avoid complications especially in exceptional cases as illustrated by our two cases.

Case Presentations: Two women had right colectomies with compete D3 mesocolon excision via laparotomy for right colon tumors with a non-modal anatomy: an X-shaped relationship between the superior mesenteric artery and the superior mesenteric vein and a Y-shaped superior mesenteric vein, an ileocolic artery behind the two trunks, a right colic artery behind the left trunk, and the middle colic artery anterior to the main trunk of the superior mesenteric vein respectively.

Discussion: Our cases illustrated extremely rare vascular variants during right colectomy with complete mesocolic excision.