[Systemic nocardiosis with mediastinal lymph node involvement proven by endoscopic ultrasound].

Introduction: Systemic nocardiosis is an infectious disease that is rarely associated with mediastinal lymph nodes.

Case Report: We report the case of a 72-year-old male patient treated with a high dose of oral corticosteroids for rheumatoid polyarthritis. This patient presented with rapid overall deterioration associated with mediastinal lymph nodes.

Caroli's Syndrome: An Early Presentation.

Fibropolycystic liver disorders (FLD) arise from abnormal development of the ductal plate and are classified according to the size of the affected hepatobiliary duct. Congenital hepatic fibrosis (CHF) has small duct involvement characterized by a variable degree of periportal fibrosis and hyperplasia without affecting the liver's architecture. Caroli's disease (CD) is a rare autosomal recessive disorder with a prevalence of one case per 1,000,000 people and is characterized by cystic dilation of large intrahepatic ducts.

Beyond the Tip of the Blade: An Investigation of Upper Extremity Machete Injuries in Honduras.

Background:  Machete injuries constitute a major cause of morbidity in Honduras. In this study, we aimed to determine the incidence, initial management, surgical treatment, and follow-up patterns for machete injuries at the national public hospital in Honduras. Microsurgery in Honduras is currently in transition with limitations at multiple levels.

Clinical ACO phenotypes: Description of a heterogeneous entity.

Background: Because ACO (Asthma-COPD-Overlap) does not fill out asthma or COPD (Chronic Obstructive Pulmonary Disease) criteria, such patients are poorly evaluated. The aim of this study was to screen asthma and COPD for an alternative diagnosis of ACO, then to determine subgroups of patients, using cluster analysis.

Material And Methods: Using GINA-GOLD stepwise approach, asthmatics and COPD were screened for ACO.

HCN3 ion channels: roles in sensory neuronal excitability and pain.

Key Points: HCN ion channels conducting the I current control the frequency of firing in peripheral sensory neurons signalling pain. Previous studies have demonstrated a major role for the HCN2 subunit in chronic pain but the potential involvement of HCN3 in pain has not been investigated. HCN3 was found to be widely expressed in all classes of sensory neurons (small, medium, large) where it contributes to I .