Publications by authors named "S Labied"

Article Synopsis
  • Fertilized zygotes usually have two pronuclei (PN), but abnormalities like 1PN zygotes are common in IVF, leading to debates on whether to transfer them. This study investigated neonatal outcomes from 1PN zygotes using two fertilization methods: conventional IVF (cIVF) and intracytoplasmic sperm injection (ICSI) across several years.
  • Data from 1234 fresh 1PN zygotes indicated a higher quality embryo development and blastulation rate in the cIVF group (46% and 44%, respectively) compared to the ICSI group (33% and 20%). Additionally, pregnancy rates were higher in the cIVF group despite both methods
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BCL6 (B-cell lymphoma 6) is a proto-oncogene and transcriptional repressor initially described as being involved in B-cell lymphoma. Recently, this factor has been identified as a promising tissue biomarker which could be used to diagnose women affected by endometriosis. Previous studies used HSCORE for BCL6 staining quantification in the endometrium.

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The rise of oocytes cryopreservation (OOC) in assisted reproductive techniques allows fertility preservation (FP) in an increasing number of indications. Endometriosis, a highly prevalent disease, potentially impairing ovarian reserve, seems, therefore, an interesting indication for it. The purpose of this study is to summarize the available evidence concerning FP by OOC in women with endometriosis and to calculate the number needed to treat (NNT).

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Background: Preservation of female fertility is a relatively new field in medicine that has grown very rapidly in recent decades. At the beginning, embryo freezing remained the most effective technique. Thereafter, cryopreservation of oocytes and ovarian tissue was considered a secure tool in human fertility preservation.

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