Publications by authors named "S Labib"

Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is a rare condition in children that causes acute, severe, but often reversible systolic dysfunction of the left ventricle. Physical trauma is a recognized trigger, although distinguishing TTC from myocardial contusion in pediatric trauma cases can be challenging due to overlapping clinical features. We present the case of a six-year-old boy involved in a high-impact motor vehicle collision.

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Background: Glucagon like peptide-1 receptor agonists (GLP-1RA) promote weight loss and improve heart failure-related symptoms, quality of life, and functional capacity in patients with obesity and heart failure with preserved ejection fraction (HFpEF). However, their clinical effectiveness in non-obese patients with diabetes and HFpEF is understudied.

Methods: The TriNetX research network was used to identify adult patients (≥18 years) with type 2 diabetes mellitus (T2DM), Heart failure with preserved ejection fraction ((Left ventricular ejection fraction ≥45%), elevated brain natriuretic peptide (≥150pg/mL) or N-terminal pro-B-type natriuretic peptide(≥450pg/mL) and a body mass index (BMI) <30 kg/m2 on or before August 31, 2022.

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Graft selection for ACL reconstruction remains controversial. In addition, an increasing number of ACL reconstructions (ACLR) are being performed in an aging population, creating a potential gap in evidence. The goal is to restore functional stability to the knee, minimize the likelihood of graft failure, and provide patient satisfaction achieved primarily by a patient's ability to return to unrestricted physical activity.

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Article Synopsis
  • - The study investigated the roles of long noncoding RNAs (NEAT1), microRNAs (miR-21), and cytokine (IL-17) in Behçet's disease (BD) by comparing their levels in Egyptian BD patients to healthy individuals.
  • - Findings revealed that NEAT1 and miR-21 were downregulated and IL-17 was upregulated in BD patients, with IL-17 showing significant correlations with certain disease manifestations and treatments.
  • - The research suggests that these molecules could be important in understanding BD's pathogenesis, indicating a need for further studies to explore their potential as biomarkers or therapeutic targets.
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Erythromelalgia is a rare neurovascular condition characterized by episodic burning pain, erythema, and increased temperature of the extremities. This condition, particularly challenging in pediatric patients due to its rarity and the complexities of pain management, often results in significant distress and impaired quality of life. We report the case of a 14-year-old patient who presented with severe primary erythromelalgia.

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