Publications by authors named "S La Maestra"
The World Health Organization has confirmed that asbestos fibres are carcinogenic, claiming that asbestos-related diseases should be eradicated worldwide. Actinolite, amosite, anthophyllite, chrysotile, crocidolite, and tremolite are regulated asbestiform mineral phases. However, in nature, asbestos minerals occur either in a fibrous and asbestiform (original morphology characterized by high length-to-width ratio and provided of high tensile strength and flexibility) or fibrous but not asbestiform appearance.
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- * In this study, human kidney cells exposed to both polyethylene microplastics and BPA showed decreased cell viability and increased pro-oxidant and pro-inflammatory responses compared to those exposed to either substance alone.
- * Additionally, the research found that exposure reduced levels of heat shock protein (HSP90) while increasing aryl hydrocarbon receptor (AHR) expression, highlighting the need for further investigation into how these pollutants interact and affect kidney health.
Article Synopsis
- DNA damage is a key factor in cancer and chronic diseases, making early detection in affected cells essential for understanding and preventing these conditions.
- Evaluating genotoxic damage in alveolar macrophages serves as a practical method to assess this damage since they closely interact with lung cells and are easily obtainable.
- Studies using these macrophages enhance our understanding of DNA damage mechanisms in the lungs, which can inform risk management and support cancer chemoprevention efforts.
(MC), a member of the complex, can cause infections in patients after open-heart surgery due to contaminated heater-cooler units (HCUs). The transmission route of HCU-related MC infection is non-inhalational, and infection can occur in patients without previously known immune deficiency. Patients may develop endocarditis of the prosthetic valve, infection of the vascular graft, and/or manifestations of disseminated mycobacterial infection (splenomegaly, arthritis, hepatitis, nephritis, myocarditis, etc.
View Article and Find Full Text PDFUVB-Aged Microplastics and Cellular Damage: An in Vitro Study.
Arch Environ Contam Toxicol
July 2024
Plastics are synthetic organic compounds whose widespread use generates enormous waste. Different processes, such as mechanical abrasion, microbiological activity, and UVB irradiation, can fragment the plastic material and generate microplastics (MPs). MPs are ubiquitous, and various organisms, including humans, can ingest or inhale them, with potential adverse health effects.
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