Chronic oral safety study of the aqueous extract of Combretum molle twigs on biochemical, haematological and antioxidant parameters of Wistar rats.

Background: Combretum molle R.B/G. Don (Combretaceae) is a graceful deciduous shrub, distributed especially in tropical Africa and used in traditional medicine in the treatment of malaria, diabetes, and bacterial, liver and cardiovascular deseases.

Antioxidant Properties and Digestive Enzyme Inhibitory Activity of the Aqueous Extract from Leafy Stems of .

(Vitaceae) is a plant used in Cameroonian traditional medicine for the treatment of diabetes. The aims of this study were to evaluate the in vitro antioxidant and antidiabetic activities of the aqueous extract of leafy stems. The enzyme inhibitory activity was determined in vitro on -amylase and -glucosidase enzymes, followed by confirmative study in vivo on normal rats (oral starch and sucrose tolerance tests at doses of 111, 222, and 444 mg/kg).

Endothelium nitric oxide-independent vasorelaxant effects of the aqueous extract from Stephania abyssinica on the isolated rat thoracic aorta.

Background: Stephania abyssinica (Dillon & A. Rich) Walp (Menispermaceae) is a medicinal plant used in the west region of Cameroon to treat arterial hypertension. The present study evaluated the vasorelaxant effects of the aqueous (AESA) and methanol (MESA) extracts from the fresh leaves of S.

In vitro anti-hyperglycemic and antioxidant properties of extracts from the stem bark of Ceiba pentandra.

Background: The goal of the study was to determine the antidiabetic mechanisms and the antioxidant effects of aqueous (decoction and maceration) and methanol extracts from the stem bark of Ceiba pentandra.

Methods: These extracts were tested in vitro on glucose uptake by skeletal muscles and liver slices and on glucose release by liver slices. The antioxidant activities of C.

In vivo antioxidant and vasodilating activities of Gmelina arborea (Verberaceae) leaves hexane extract.

The present study investigated the effects of Gmelina arborea hexane leaves extract on markers of oxidative stress and its vasorelaxant effects on isolated rat aorta, in order to postulate the possible mechanisms involved in the antihypertensive properties of the plant. To evaluate the antioxidant effects of the extract, rats were randomly divided into four groups of five rats each. With the exception to the group receiving Tween (2.