Publications by authors named "S L STEELMAN"

Background: Recurrent burn contractures on the volar aspect of the hand present a formidable challenge, especially in the pediatric patient. We used Integra followed by staged full-thickness skin grafting for recurrent bilateral volar hand burn contracture in a toddler. We reviewed the literature to appraise the utility of full-thickness skin graft (FTSG) combined with Integra used for volar hand contractures.

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Fever is the most common complaint for children of all ages who present to an emergency department (ED) for evaluation and treatment. Although most children with fever have a self-limiting viral illness, the infant less than 60 days of age with fever poses a higher risk for an underlying serious bacterial illness (SBI) including urinary tract infections, bacteremia and bacterial meningitis, or an invasive bacterial infection (IBI) including bacteremia. This case is a discussion of a high-risk febrile infant that was evaluated in the emergency department and was ultimately diagnosed with Streptococcus B meningitis.

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Objective: This study aims to evaluate the success rates and complications associated with different free flap donor sites used in surgical reconstruction for mandibular osteoradionecrosis, providing insights to aid clinical decision-making.

Data Sources: MEDLINE, Embase, Cochrane, and Web of Science.

Review Methods: Comprehensive database searches were conducted up to October 2023.

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Objective: To analyse amniotic fluid volume (AFV), specifically oligohydramnios or polyhydramnios, and associated pregnancy and neonatal outcomes in twin gestations through systematic review and meta-analysis.

Methods: We utilised systematic review methodology to identify items within published and grey literature resources. Prospective and retrospective studies with a control group were included.

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Article Synopsis
  • The study focuses on the role of noncoding genetic variants linked to complex traits, specifically examining how these variants affect gene-regulatory activity in different tissues using epigenomic analysis of histone marks.* -
  • Researchers analyzed data from 387 samples to identify 282,000 active regulatory elements (AREs), including 2,436 sex-biased and 5,397 genetically influenced AREs connected to 130,000 genetic variants (haQTLs).* -
  • The findings integrate genetic and epigenomic data to enhance understanding of disease-associated genetic loci and prioritize genetic circuits related to traits like schizophrenia through mechanisms such as gene linking scores (gLink scores).*
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