Publications by authors named "S L Percival"
Background: Surgical site infections (SSIs) have been shown to increase patient morbidity and mortality, impact on quality of life and place a significant economic burden on healthcare systems worldwide. Irrigation using wound cleansing and antiseptic effective solutions during surgical procedures is a key part of SSI prevention. The optimal solution would have minimal cytotoxicity to the patient while maintaining a minimum concentration required for antimicrobial activity necessary to prevent opportunistic pathogens and biofilm formation.
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- Eschar and slough in wounds contribute to persistent inflammation and infection risks by harboring microorganisms, biofilms, and inflammatory substances.
- This study developed an in vitro model simulating wound conditions with artificial slough to test the effectiveness of a new antibacterial technology featuring silver-zinc EDTA complexes.
- Findings indicate that this new technology can effectively disrupt biofilms and may be beneficial in treating chronic wound infections.
Exceptional Electrical Detection of Trace NO via Mixed Metal MOF-on-MOF Film-Based Sensors.
ACS Appl Mater Interfaces
November 2024
The tunability of metal-organic frameworks (MOFs) makes them exceptional materials for the development of highly selective, low-power sensors for toxic gas detection. Herein, we demonstrate enhanced detection of NO gas by a MOF-based electrical impedance sensor made using a unique mixed metal MOF-on-MOF synthesis. A combined experimental and computational study was performed using the exemplar NiMg-MOF-74 to understand the fundamental structure-property relationships behind metal mixing and MOF film synthesis methods on sensor performance.
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- The way electrons are shot out from a source depends a lot on how the laser is shaped when it hits the material.
- Using a special mask to shape the laser can be tricky because it can't perfectly recreate the sharp edges we want.
- This study found that the way the laser travels through small openings can create uneven patterns, and while these patterns usually don't change the overall statistics, they might still cause problems for machines that use these electron bunches.