Publications by authors named "S L Paulson"
Background: Maternal vaccination and infant monoclonal antibodies are promising avenues to protect young infants from respiratory syncytial virus (RSV) infection. Successful inclusion into the UK immunization schedule depends on parental acceptability, among other factors.
Methods: An online cross-sectional survey from August to September 2023 exploring the likelihood of accepting, and preference for, either method of RSV prophylaxis, and reasons given for these.
Open scientific competitions have successfully driven biomedical advances but remain underutilized in aging research, where biological complexity and heterogeneity require methodological innovations. Here, we present the results from Phase I of the Biomarkers of Aging Challenge, an open competition designed to drive innovation in aging biomarker development and validation. The challenge leverages a unique DNA methylation dataset and aging outcomes from 500 individuals, aged 18 to 99.
View Article and Find Full Text PDFChikungunya virus (CHIKV) and Mayaro virus (MAYV) are emerging/re-emerging alphaviruses transmitted by Aedes spp. mosquitoes and responsible for recent disease outbreaks in the Americas. The capacity of these viruses to cause epidemics is frequently associated with increased mosquito transmission, which in turn is governed by virus-host-vector interactions.
View Article and Find Full Text PDFBackground: A growing body of research has examined lifestyle-based interventions for dementia prevention. Specifically, health coaching interventions have been linked to decreased risk of Alzheimer disease (AD) comorbidities, such as diabetes. Despite the association, there is a lack of research examining the efficacy and perception of digital health coaching on reducing AD risk.
View Article and Find Full Text PDFArticle Synopsis
- Prenatal exposure to traffic-related particulate matter (PM2.5) may lead to oxidative stress, potentially affecting birth outcomes in infants.* -
- The study analyzed urine samples from 156 pregnant women to measure biomarkers of oxidative stress, specifically malondialdehyde (MDA) and 8-hydroxy-2'-deoxyguanosine (8-OHdG), in relation to PM2.5 exposure.* -
- Findings revealed a significant increase in oxidative stress biomarkers during mid-pregnancy linked to higher levels of PM2.5 and black carbon, suggesting that air pollution is a concern during early to mid-pregnancy.*