Publications by authors named "S L Marchesi"

Background: One in four patients with moderate to severe traumatic brain injury (TBI) also has other body district injuries (OBD). The impact of OBD on mortality and disability is debated. This study compared outcomes of TBI patients with polytrauma (p-TBI) versus isolated TBI (alone-TBI) and identified outcome determinants, focusing on survival time and prognosis.

View Article and Find Full Text PDF
Article Synopsis
  • Paclitaxel plus ramucirumab is being evaluated as a second-line treatment for patients with advanced HER2-negative gastric or gastro-oesophageal junction cancer, comparing it with continued oxaliplatin and fluoropyrimidine chemotherapy.
  • The ARMANI trial involved 280 patients, who were randomly assigned to receive either the new treatment regimen or continue with their current chemotherapy for an additional 12 weeks.
  • The primary goal of the study was to determine if the new treatment improved progression-free survival compared to the standard chemotherapy, with safety being closely monitored throughout the trial.
View Article and Find Full Text PDF

A synthetic saponite clay containing structural Nb(V) metal centres (NbSAP) was investigated in the abatement of paraoxon-ethyl, an anti-cholinergic organophosphorus pesticide, under mild conditions (neutral pH, room temperature and ambient pressure) in heterogenous phase, without additional basic additives. The material was selected according to its high surface acidity and ease of preparation through a one-step hydrothermal synthesis. The presence of Nb(V) ions played a crucial role in efficiently catalysing the degradation of aggressive chemical substrates.

View Article and Find Full Text PDF

Mesothelioma is a malignant tumor associated primarily with asbestos exposure, characterized by an aggressive nature and poor prognosis. Accurate diagnosis, staging, and monitoring of therapeutic response are crucial for effective patient management. Along with a computed tomography (CT) scan, fluorodeoxyglucose labeled with fluorine-18 ([F]FDG) positron emission tomography (PET) is commonly used in mesothelioma evaluation.

View Article and Find Full Text PDF