Behavioural interventions to increase uptake of FIT colorectal screening in Scotland (TEMPO): a nationwide, eight-arm, factorial, randomised controlled trial.

Background: Uptake of colorectal cancer screening is suboptimal. The TEMPO trial evaluated the impact of two evidence-based, theory-informed, and co-designed behavioural interventions on uptake of faecal immunochemical test (FIT) colorectal screening.

Methods: TEMPO was a 2 × 4 factorial, eight-arm, randomised controlled trial embedded in the nationwide Scottish Bowel Screening Programme.

Visitor effects on the welfare of captive Sumatran orangutans () during the pandemic lockdowns.

The COVID-19 pandemic led to unprecedented lockdowns with rippling impacts on the lives of humans and animals alike. Since zoos were among the first institutions to close during the pandemic, the lockdowns presented the opportunity to conduct a natural experiment examining the relationship between visitor presence and the welfare of zoo-housed animals. In this study, we assessed the welfare of six Sumatran orangutans () at Toronto Zoo both during and following the pandemic lockdowns.

Changes in Vasectomy Practice Patterns After-Dobbs: A Multi-Institutional Study.

Importance: Following the Dobbs decision overruling Roe vs. Wade, public interest in vasectomies increased. This ruling directly impacted urologic practice patterns, and warrants further investigation.

Beyond Mute and Block: Adoption and Effectiveness of Safety Tools in Social VR, from Ubiquitous Harassment to Social Sculpting.

Harassment in Social Virtual Reality (SVR) is a growing concern. The current SVR landscape features inconsistent access to non-standardised safety features, with minimal empirical evidence on their real-world effectiveness, usage and impact. We examine the use and effectiveness of safety tools across 12 popular SVR platforms by surveying 100 users about their experiences of different types of harassment and their use of features like muting, blocking, personal spaces and safety gestures.

Treatment Approach for Metastatic Intracranial Germinoma: A Multi-Institutional Experience.

Background: Germinoma is the most common intracranial germ cell tumor (IGCT) in children and young adults. Treatment with 24 Gy craniospinal irradiation (CSI) with boost to 40 Gy alone results in excellent survival, irrespective of disease stage. For localized germinoma, recent studies have demonstrated the efficacy of pre-irradiation induction chemotherapy in decreasing the field and dose of radiation therapy (RT) needed for cure.