Publications by authors named "S L Lake"

Although several studies have well described the characteristics of people who use psychedelics alongside their motivations and beliefs, little research has examined the preferences surrounding the source of psychedelic substances. In an anonymous online survey, we collected data from 6,379 consumers of 11 different psychedelic substances from 85 different countries, exploring their preferences and perceptions on natural and synthetic psychedelics. There was a strong preference of natural sources over synthetic alternatives for psilocybin (75%), DMT (56%), and mescaline (56%).

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Article Synopsis
  • - The study developed a shortened version of the Awe Experience Scale (AWE-SF) to make it easier for participants while keeping its accuracy intact, using data collected from psychedelic samples across five different studies.
  • - The AWE-SF kept the original six-factor structure of the longer AWE-S and was validated by showing strong connections to positive emotions, mystical experiences, and overall well-being.
  • - Specific elements of awe, like feelings of connection or vastness, were linked to positive feelings, while aspects like self-loss were tied to more challenging experiences; overall, the AWE-SF proved effective as a tool for measuring awe experiences.
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Despite psychedelic microdosing being a growing practice, the research on the topic is still in its infancy. While several studies have described the characteristics, motivations and practices of microdosers, the differences between individuals that only microdose and those that use both micro and macrodoses of psychedelics remain unexplored. In an online survey, we collected data of 6193 psychedelic consumers of which 2488 were microdosers of up to 11 different classical and atypical psychedelics.

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Background/aims: While most psychedelic substances are considered to carry a relatively low risk of acute or long-term harm, co-use with other psychoactive substances may increase health and social harm. Using a large international survey of adults who use psychedelics, we sought to comprehensively characterize psychedelic co-use.

Methods: We used data from the 2023 Global Psychedelic Survey, a web-based survey of adults ⩾21 with lifetime use of psychedelics.

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Article Synopsis
  • The study compared treatment costs and clinical outcomes for retinal surgery patients in Darwin, either treated locally or transferred to tertiary centers.
  • A total of 70 patients' cases were analyzed, revealing that most transfers involved retinal detachment, while local patients had various conditions.
  • Results indicated similar surgical success rates and complications between both groups, with only minimal and insignificant cost differences.
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