First case report of effective and safe application of cannabidiol to treat concurrent ALG3-CDG and Lennox-Gastaut Syndrome.

This study presents the first reported case of a Korean patient with Alpha-1,3-Mannosyltransferase-Congenital Disorder of Glycosylation (ALG3-CDG), characterized by a novel maternally inherited missense mutation and a previously reported paternally inherited nonsense mutation. The patient exhibited typical ALG3-CDG manifestations, including developmental delays, epilepsy, and multisystem involvement, alongside a diagnosis of Lennox-Gastaut Syndrome (LGS). Cannabidiol therapy, combined with dietary management, led to seizure freedom for over 13 months, significant EEG improvement, and enhanced developmental outcomes.

Surfactant-based interface capture towards the development of 2D-printed photonic structures.

This study focuses on fabricating photonic crystals (PCs) by surfactant-based particle capture at the gas-liquid interface of evaporating sessile droplets. The captured particles form interfacial films, resulting in ordered monolayer depositions manifesting iridescent structural colors. The particle dynamics behind the ordered arrangement is delineated.

Task loading of soldering workers in small-scale manufacturing units.

Soldering is common in electrical product manufacturing, but the task load in small units is unquantified. Therefore, this study aimed to establish the occurrence of task load due to soldering work, analyzing the effects of age and sex among workers in small manufacturing units. The task load of 102 soldering workers from four small-scale manufacturing units was assessed using the National Aeronautics and Space Administration task load index (NASA-TLX) questionnaire, covering six dimensions: physical demand, mental demand, temporal demand, effort, performance and frustration.

Leveraging regulatory fit to enhance engagement: a public-sector study in South Korea.

This study extends the Job Demands-Resources (JD-R) model by incorporating regulatory focus (promotion vs. prevention) as a moderator, examining its impact on job engagement among public sector employees ( = 306). The results show that employees with a promotion focus are more likely to experience increased engagement when facing challenge stressors, as they perceive such stressors as growth opportunities.

Enhancing molecular oxygen activation by nitrogen-doped carbon encapsulating FeNi alloys with ultra-low Pt loading.

Modulating the electronic structure of noble metals via electronic metal-support interaction (EMSI) has been proven effectively for facilitating molecular oxygen activation and catalytic oxidation reactions. Nevertheless, the investigation of the fundamental mechanisms underlying activity enhancement has primarily focused on metal oxides as supports, especially in the catalytic degradation of volatile organic compounds. In this study, a novel Pt catalyst supported on nitrogen-doped carbon encapsulating FeNi alloy, featuring ultrafine Pt nanoparticles, was synthesized.