Detection of human noroviruses in sewage by next generation sequencing in Shandong Province, 2019-2021.

Background: Human noroviruses are the major cause of acute gastroenteritis and exhibit considerable genetic diversity. Next generation sequencing (NGS) analysis based on environmental surveillance has been proved to be an effective method in norovirus surveillance.

Methods: Between January 2019 and December 2021, 36 sewage samples were collected and analyzed using real-time quantitative PCR to detect noroviruses.

Higher monomeric C-reactive protein levels are associated with premature coronary artery disease.

Introduction: Chronic inflammation is a major risk factor for coronary artery disease (CAD). Currently, the inflammatory cardiovascular risk is assessed via C-reactive protein (CRP) levels measured using a high-sensitivity assay (hsCRP). Monomeric CRP (mCRP) is a locally produced form of CRP that has emerged as a potential biomarker of inflammation.

Establishment and evaluation of rabbit model for corneal ectasia by photorefractive keratectomy.

The study aimed to compare the effects of different types of excimer laser keratectomy on rabbit corneas and to identify the optimal disease model for corneal ectasia. Additionally, investigating the structural and molecular alterations in the novel disease model helped explore the mechanisms underlying biomechanical cues in corneal ectasia. 2.

Structural Regulation and Performance Enhancement of Carbon-Based Supercapacitors: Insights into Electrode Material Engineering.

The development of carbon-based supercapacitors is pivotal for advancing high energy and power density applications. This review provides a comprehensive analysis of structural regulation and performance enhancement strategies in carbon-based supercapacitors, focusing on electrode material engineering. Key areas explored include pore structure optimization, heteroatom doping, intrinsic defect engineering, and surface/interface modifications.

Effects of perfluorolauric acid exposure on intestinal microbial community and physiological health indicators in mice.

The present study aims to investigate the effects of Perfluorolauric Acid (PFLA) on the gut microbiota community and the physiological health of mice. The experiment was conducted by setting a control group (CTRL) and an experimental group (PFLA), exposing mice to PFLA and observing changes in their gut microbiota community and physiological health indicators. The results showed that exposure to PFLA significantly altered the β diversity of the gut microbiota in mice, as evidenced by NMDS, PCoA, and PCA analyses, indicating a clear change in microbial community structure between the PFLA group and the CTRL group.