[Use of psychotropic drugs among Indigenous and Quilombola communities in Brazil].

The use of psychotropic drugs has become a public health issue due to their high consumption worldwide. In the context of traditional populations, the literature on the use of these medications is scarce. This study presents a descriptive analysis of psychotropic drug use among Indigenous and Quilombola communities in the states of Minas Gerais, Rio Grande do Norte, Alagoas, and Piauí in Brazil.

Chia Oil Nanoemulsion Using Chia Mucilage as a Wall Material: An Alternative for Cracker Fat Substitution.

Crackers are bakery products that have shown an increase in consumption. One way to make crackers more nutritious is to add bioactive compounds, such as chia oil which is rich in polyunsaturated fatty acids. As these compounds are highly unsaturated, encapsulation techniques, such as nanoemulsion, allow the addition of them in foods, guaranteeing the preservation of their properties.

Matrix of interprofessional competencies in multiprofessional health residencies: construction of a proposal.

Objective: To construct a matrix of interprofessional competencies produced in Multiprofessional Health Residencies in the interior of Rio Grande do Norte.

Method: Qualitative study, with a deductive method for theorization and construction of the competency matrix. It was organized into three phases: theoretical, field and analytical phase.

Phase II Study of Acalabrutinib, Venetoclax, and Obinutuzumab in a Treatment-Naïve Chronic Lymphocytic Leukemia Population Enriched for High-Risk Disease.

Purpose: The AMPLIFY trial recently established fixed-duration acalabrutinib, venetoclax, and obinutuzumab (AVO) as a new standard-of-care option for patients with previously untreated chronic lymphocytic leukemia (CLL) with wild-type ; however, due to the chemoimmunotherapy control arm, AMPLIFY excluded patients with high-risk aberration, for whom current standards of care are continuous Bruton tyrosine kinase inhibitor therapy or alternatively fixed-duration venetoclax-based doublets. AVO has not previously been evaluated in patients with CLL with aberration.

Methods: This investigator-sponsored, multicenter, phase II study enrolled patients with treatment-naïve CLL enriched for high-risk CLL, defined by aberration (ClinicalTrials.