Na and Cl adsorption derived enhancement in 4-nitrophenol reduction using Au/Ag nanoparticle: An experimental and theoretical study.

4-Nitrophenol (4-NP) is an organic contaminant attached to textiles, pharmaceuticals, and pesticides. Its presence has been increasingly detected in various water bodies such as lakes, rivers, and occasionally in drinking water. The present work shows the reduction of 4-NP using a hybrid catalytic system composed of gold and silver nanoparticles supported onto the biogenic porous silica (AgAu-SiO).

Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.

Background: The glucocorticoid receptor (GR) is a transcription factor that regulates gene expression in a ligand-dependent fashion. This modular protein is one of the major pharmacological targets due to its involvement in both cause and treatment of many human diseases. Intense efforts have been made to get information about the molecular basis of GR activity.