Resting After Learning Facilitates Memory Consolidation and Reverses Spatial Reorientation Impairments in 'New Surroundings' in 3xTg-AD Mice.

Sleep is an essential component of productive memory consolidation and waste clearance, including pathology associated with Alzheimer's disease (AD). Facilitation of sleep decreases Aβ and tau accumulation and is important for the consolidation of spatial memories. We previously found that 6-month female 3xTg-AD mice were impaired at spatial reorientation.

Subtleties of nanophotonic lithium niobate waveguides for on-chip evanescent wave sensing.

Thin-film lithium niobate (TFLN) is promising for optical sensing due to its high nonlinearities, but its material properties present unique design challenges. We compare the sensing performance of the fundamental modes on a TFLN waveguide with a fluorescent dye sample. The TM mode has better overlap with the sample, with a 1.

The effects of moderate prenatal alcohol exposure on performance in object and spatial discrimination tasks by adult male rats.

Exposure to alcohol during pregnancy produces Fetal Alcohol Spectrum Disorders, which in its most severe form is characterized by physical dysmorphology and neurobehavioral alterations. Moderate prenatal alcohol exposure (mPAE) is known to produce deficits in discrimination of spatial locations in adulthood. However, the impact of mPAE on higher-order sensory representations, such as discrimination of perceptually similar stimuli, is currently unknown.

Feasibility and Outcomes of an Active Osseointegrated Bone Conduction Implant in Children as Young as 5 Years of Age.

Introduction: This study reviews the feasibility of implanting active osseointegrated bone conduction devices in young children, below the prior age for FDA indication (<12 years), which has recently been reduced to 5 years. Outcomes included differences in adverse event rates and operative time between two groups (<12 and 12 years or older).

Materials And Methods: This study is a retrospective review of children receiving active osseointegrated bone conduction devices at a tertiary referral center academic hospital.

Laser-driven ultrafast impedance spectroscopy for measuring complex ion hopping processes.

Superionic conductors, or solid-state ion-conductors surpassing 0.01 S/cm in conductivity, can enable more energy dense batteries, robust artificial ion pumps, and optimized fuel cells. However, tailoring superionic conductors requires precise knowledge of ion migration mechanisms that are still not well understood due to limitations set by available spectroscopic tools.