Nanoparticles embedded in polymer matrices play a critical role in enhancing the properties and functionalities of composite materials. Detecting and quantifying nanoparticles from optical images (fixed samples-in vitro imaging) is crucial for understanding their distribution, aggregation, and interactions, which can lead to advancements in nanotechnology, materials science, and biomedical research. In this article, we propose an ensembled deep learning approach for automatic nanoparticle detection and oligomerization quantification in a polymer matrix for optical images.
View Article and Find Full Text PDFJ Clin Orthop Trauma
February 2025
A wide variety of degenerative, inflammatory and infective arthropathies with overlapping clinical features can involve the knee joint. Due to its excellent soft tissue contrast resolution and multiplanar capability, magnetic resonance imaging (MRI) plays a significant role in early and accurate diagnosis of various arthropathies. In this article, we have provided a brief review of MRI features of various arthropathies involving the knee joint.
View Article and Find Full Text PDFBackground: Clear cell renal cell carcinoma (ccRCC) is a prevalent and aggressive malignancy, with the von Hippel-Lindau (VHL) gene playing a critical role in its pathogenesis. However, the association between VHL gene variants and sporadic ccRCC risk remains unexplored in the Indian population. This study aimed to investigate the somatic and germline variants of the VHL gene in sporadic ccRCC patients from West Bengal, India, and their association with disease risk and clinicopathological parameters.
View Article and Find Full Text PDFBackground: Antimicrobial resistance (AMR) is a global health and development concern. Antimicrobial misuse and overuse are key contributors to the emergence of drug-resistant infections.
Objective: The current study aimed to determine the level of perception and practices of physicians regarding AMR in a tertiary-level hospital.
Introduction Chronic obstructive pulmonary disease (COPD) is a significant contributor to global morbidity and mortality. Despite well-established management protocols, treatment remains suboptimal due to high costs and mortality rates. This study aims to compare the impact of initial oxygenation status, Dyspnea, Eosinopenia, Consolidation, Acidemia, and Atrial Fibrillation (DECAF), and National Early Warning Score 2 (NEWS2) scores on management outcomes in COPD patients.
View Article and Find Full Text PDF