Publications by authors named "S Kyo"

Article Synopsis
  • The study aimed to assess the effectiveness and safety of robot-assisted radical hysterectomy (RARH) in treating cervical cancer, comparing it to traditional surgical methods.
  • A total of 100 patients underwent RARH, achieving a high success rate with minimal blood loss and low recurrence rates after 2 years.
  • Results showed strong oncological outcomes, with RARH yielding excellent recurrence-free survival (RFS) and overall survival (OS) rates, suggesting its viability as a surgical option for cervical cancer.
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Article Synopsis
  • Ovarian cancer is categorized into two types: low-grade serous carcinoma (LGSC), which arises from serous borderline tumors (SBT), and high-grade serous carcinoma (HGSC), typically originating from serous tubal intraepithelial carcinoma (STIC).
  • The case study discusses a patient diagnosed with stage IIIC HGSC, who also had SBT and LGSC, highlighting the complexities in the cancer's development and treatment.
  • Despite undergoing surgery and chemotherapy (TC + bevacizumab), the tumor was resistant to treatment and exhibited mutations, with p53 dysfunction believed to play a role in the transformation from SBT/LGSC to HGSC.
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Background: AT-rich interaction domain 1A (ARID1A) has been proposed as a new biomarker for predicting response to immune checkpoint inhibitors (ICIs). The predictive value of ARID1A for predicting ICI effectiveness has not been reported for endometrial cancer. Therefore, we investigated whether ARID1A negativity predicts ICI effectiveness for endometrial cancer treatment.

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