Publications by authors named "S Kurisu"

Atrial natriuretic peptide (ANP) is a circulating hormone released from the atria in response to wall stretch and volume overload in the setting of heart failure. When atrial fibrillation (AF) becomes long-standing persistent, ANP secretion in response to volume overload is impaired due to degenerative changes of the atria. Here, we report a case of heart failure with preserved ejection fraction and impaired ANP secretion due to long-standing AF.

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Article Synopsis
  • * A case study highlights a very elderly patient with dementia and atrial fibrillation who developed recurrent thrombosis, complicating the management due to his multiple health issues.
  • * The report emphasizes the need for physicians to consider age-related factors like cognitive impairment and frailty to tailor treatment goals and improve health outcomes while reducing risks in older patients with complex conditions.
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Thiamine deficiency can cause various clinical manifestations. Wet beriberi, a phenotype of thiamine deficiency, is often underdiagnosed in clinical practice due to the nonspecificity of symptoms. An 83-year-old man presented to a primary care clinic with a two-month history of progressing edema in the scrotum and lower extremities.

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Regional wall motion abnormality in the left ventricular (LV) apex detected on transthoracic echocardiography is commonly interpreted as the presence of a distal left anterior descending (LAD) artery lesion in clinical practice. Herein, we reported a rare case of apical acute myocardial infarction (AMI) caused by an occluded posterior descending branch of the right coronary artery (RCA), in which the correspondence between coronary arterial anatomy and supplied LV apex was evaluated by multi-imaging modalities. Despite the presence of regional wall motion abnormality in the LV apex, left coronary angiography showed no significant coronary artery diseases.

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Article Synopsis
  • Wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) is a progressive heart disease marked by thickening of the heart walls and is frequently linked to monoclonal gammopathy of undetermined significance (MGUS).
  • A case study is presented involving a 72-year-old man with ATTRwt-CA and M-protein who developed deep vein thrombosis (DVT) and severe left ventricular hypertrophy.
  • The diagnosis was confirmed through various tests, including heart scans and a biopsy, highlighting the importance for clinicians to recognize the connection between ATTRwt-CA, M-protein, and the risk of thrombotic events like DVT.
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