Evaluation of Mechanochemically Prepared CePO∙HO Nanoparticles as UV Filter for Photoprotective Formulations.

Rhabdophane, CePO∙HO, nanoparticles were prepared by mechanochemical synthesis with different durations and thoroughly characterized by various characterization techniques. X-ray diffraction analysis showed that the optimal synthesis duration was 15 min, since, in this case, pure rhabdophane is obtained, without traces of contamination by the vessel material. The size of the obtained nanoparticles, as determined from high-resolution transmission electron microscopy images, was around 5 nm.

Sol-Gel Synthesis of Zinc Alumotitanate, Monitoring of Chelation, Hydrolysis, Condensation, and Crystallization Processes.

Zinc alumotitanate sorbents with various compositions were prepared through sol-gel synthesis with the use of ethyl acetoacetate as a chelating agent. The formation and decomposition of chelates, providing insight into sol-gel process advancement, have been successfully monitored via H NMR, C NMR, and FTIR spectroscopy. It has been established that Al(OBu) and Ti(OBu) react completely with Eaa, forming chelates after 1 h, while after 24 h hydrolysis is already advanced.

Humidity Sensing Ceria Thin-Films.

Lowering the constitutive domains of semiconducting oxides to the nano-range has recently opened up the possibility of added benefit in the research area of sensing materials, in terms both of greater specific surface area and pore volume. Among such nanomaterials, ceria has attracted much attention; therefore, we chemically derived homogeneous ceria nanoparticle slurries. One set of samples was tape-casted onto a conducting glass substrate to form thin-films of various thicknesses, thereby avoiding demanding reaction conditions typical of physical depositions, while the other was pressed into pellets.

Phase composition, morphology, properties and improved catalytic activity of hydrothermally-derived manganese-doped ceria nanoparticles.

Manganese-doped ceria nanoparticles were prepared by hydrothermal synthesis and the prepared samples were thermally treated at 500 °C for 2 h. The samples were investigated using x-ray diffraction (XRD), high-resolution transmission electron microscopy (HR-TEM), energy-dispersive x-ray spectroscopy (EDS), Nadsorption and x-ray photoelectron spectroscopy (XPS). XRD revealed that nanocrystalline ceria is the main phase in all samples, while a romanechite-like phase (NaMnO) appears in the sample doped with 30% of Mn.

Drug-Drug Compatibility Evaluation of Sulfasalazine and Folic Acid for Fixed-Dose Combination Development Using Various Analytical Tools.

The simultaneous administration of sulfasalazine and folic acid is regular practice in the therapy of inflammatory bowel diseases in order to maintain sufficient folate concentration in patients. Having multiple drugs in the therapy increases the possibility of patients failing adherence, thus unintentionally endangering their health. A fixed-dose combination of sulfasalazine and folic would simplify the classical polytherapeutic approach; however, the physicochemical compatibility investigation of two active pharmaceutical ingredients plays an important role in the development of such a product.