Publications by authors named "S Kunene"

Background: Athletes living with disabilities (ALWDs) face various challenges including stigma, discrimination, poor access to quality services and lack of funding. Their needs are also numerous. Despite the transformative promise of 'Leave No One Behind' of the United Nations' 2030 agenda, people living with disabilities are still left behind.

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Article Synopsis
  • Nanomedicine is gaining traction for improving drug delivery methods, particularly in treating diseases, with a focus on smart supermagnetic nanocomposites made from iron oxide nanoparticles for targeted delivery of doxorubicin (DOX) to tumors.
  • X-ray diffraction (XRD) analysis confirmed that the structure of iron oxide remained unchanged during the coating process, and the developed nanocomposites showed high drug loading efficiency and capacity, especially under acidic conditions, which is beneficial for targeting tumor environments.
  • The in vitro studies indicated that these nanocomposites notably inhibited the survival of liver cancer cells, demonstrating their potential to enhance treatment outcomes compared to traditional methods.
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A new drug delivery system (DDS) type complexing magnetic nanoparticles (MNP) along with boron nanosheets (BNN) coated with a pH-responsive polymer-polyethylene glycol (PEG) for the manageable loading/release of the anti-cancerous drug, doxorubicin (DOX), was created (MNP-BNN-PEG-DOX). The X-ray diffraction patterns of the nanocomposites displayed wide diffraction peaks for BNN at 25.1° and 42.

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Dual pH-sensitive smart nanocarriers based on silica nanoparticles (SNPs) extracted from rice husk ashes (RHAs) to effectively inhibit liver cancer cell proliferation were investigated. The SNPs were coated with chitosan (CH) and loaded with doxorubicin (DOX), then functionalized with cell membrane (CM) for homologous targeting ability. The FTIR spectra showed an absorption wave number at 1083 cm which confirmed the existence of the SiOSi group, ratifying that the nanocarriers belong to silica species.

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Bambara groundnut (Vigna subterranea L. Verdc) is grown by smallholders and subsistence farmers in the marginal parts of sub-Saharan Africa. This legume is native to Africa and is cultivated throughout semi-arid sub-Saharan Africa.

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