Publications by authors named "S Kummer"
The high recurrence rate of feline meningioma despite the generally benign histomorphology warrants additional markers of clinical aggressiveness. The Ki-67 index is commonly used as prognostic marker for meningioma recurrence in people. Osteopontin (OPN) is a protein involved in tumor progression and may be a potential malignancy marker.
View Article and Find Full Text PDFContext: Congenital hyperinsulinism (CHI) is a cause of persistent hypoglycemia in childhood with considerable risk of lifelong neurological sequelae. Available pharmacological therapies are limited. Dasiglucagon is a glucagon analog for the treatment of hypoglycemia.
View Article and Find Full Text PDFBackground: Individuals with maturity-onset diabetes of the young (MODY) are often misdiagnosed as type 1 or type 2 diabetes and receive inappropriate care. We aimed to investigate the characteristics and treatment of all MODY types in a multicenter, real-world setting.
Methods: Individuals with MODY from the diabetes prospective follow-up (DPV) registry were studied.
Article Synopsis
- Ex vivo x-ray angiography enables detailed 3D imaging of blood vessels, including capillaries, by using a contrast agent to visualize the vascular structure after blood removal from organs.
- The study introduces advanced microDECT imaging protocols to analyze microvasculature while differentiating it from surrounding tissues, using specific contrast agents and counterstaining techniques.
- New workflows allow for automatic processing of images into distinct channels for skeletal tissue, vasculature, and soft tissue, enhancing the ability to analyze and investigate microvasculature in various research applications.
Article Synopsis
- Response to anticancer drugs varies among patients due to underlying biological differences, highlighting the need for identifying specific factors and biomarkers that predict drug efficacy.
- High-throughput screening platforms can help map cellular responses to anticancer agents, allowing researchers to investigate the mechanisms behind different reactions to these drugs.
- A proposed method uses ATP measurements to assess cell viability after drug treatment, facilitating the study of drug responses in both cell lines and primary cell cultures.