Publications by authors named "S Kumagai"

Article Synopsis
  • - Cone beam computed tomography (CBCT) images are useful for visualizing internal organs but often lack the image quality of treatment planning CT images, presenting a significant drawback for medical applications.
  • - A new super-resolution model called "one-shot" super-resolution (OSSR) effectively enhances CBCT image quality using minimal training data by leveraging just the target CBCT image and its matching treatment planning CT image.
  • - In tests involving pelvic images from 30 prostate cancer patients, the OSSR model showed substantial improvements in image quality metrics (RMSE, PSNR, SSIM, NMI) compared to standard methods, achieving performance similar to more data-intensive models like CycleGAN.
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Analytical pyrolysis-gas chromatography/mass spectrometry(Py-GC/MS) was chosen to quantify microplastics(MPs) in edible salts: sea salt(SS), deep-sea salt(DSS), rock salt(RS), and lake salt(LS). Samples were filtered by two-step using 20 μm(MPs20) and 1 μm(MPs1) filters. Two Py-GC/MS methods with split ratios of 100/1 for high-level and 10/1 for low-level MPs were used.

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After the report of 17 patients with occupational cholangiocarcinoma caused by long-term exposure to high concentrations of 1,2-dichloropropane and/or dichloromethane in a printing company in Osaka in 2014, additional five patients were diagnosed to have such cholangiocarcinoma. Cholangiocarcinoma was detected during regular health examination or follow-up for liver dysfunction in four of the five patients. Nearly all five patients presented with clinicopathological findings such as an elevated γ-glutamyl transpeptidase activity at the diagnosis, regional dilatation of intrahepatic bile ducts without tumor-induced obstruction, chronic bile duct injury, and precancerous/early cancerous lesions (biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct) at various sites of the bile duct.

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Article Synopsis
  • The study examined the effects of combining pembrolizumab and ramucirumab as neoadjuvant therapy for patients with PD-L1-positive non-small cell lung cancer (NSCLC).
  • Results showed a 50% major pathologic response rate among 24 patients, with six achieving complete pathologic response.
  • The combination was feasible, indicating that angiogenesis inhibitors like ramucirumab could enhance the effectiveness of immune checkpoint inhibitors against tumors.
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