Spectral investigation and characterization of host-guest inclusion complex of 4,4'-methylene-bis(2-chloroaniline) with beta-cyclodextrin.

The host-guest inclusion complex of 4,4'-methylene-bis(2-chloroaniline) (MBCA) with beta-cyclodextrin (β-CD) was prepared by co-precipitation method and characterized using absorption, fluorescence, fourier transform infrared, differential scanning calorimetry, scanning electron microscopy, atomic force microscopy and X-ray diffraction. The spectral shifts revealed that the aniline ring of 4,4'-methylene-bis(2-chloroaniline) was entrapped in the beta-cyclodextrin cavity. Nano second time resolved fluorescence studies revealed that 4,4'-methylene-bis(2-chloroaniline) exhibits single exponential decay in aqueous medium and bi-exponential in beta-cyclodextrin medium confirmed the formation of 1:1 inclusion complex.