Publications by authors named "S Kotagal"
Article Synopsis
- There is a growing need for practical guidelines for clinicians on using melatonin to treat insomnia in children with autism and neurogenetic disorders, as current data is insufficient.
- The International Pediatric Sleep Association (IPSA) formed a task force to review clinical trial literature on melatonin from 2012 onward.
- This publication summarizes evidence on melatonin's effectiveness, possible side effects, and important considerations for its use in this specific population.
Objectives: We used a high-throughput assay of 5000 plasma proteins to identify biomarkers associated with periodic limb movements (PLM) and restless legs syndrome (RLS) in adults.
Methods: Participants (n = 1410) of the Stanford Technology Analytics and Genomics in Sleep (STAGES) study had blood collected, completed a sleep questionnaire, and underwent overnight polysomnography with the scoring of PLMs. An aptamer-based array (SomaScan) was used to quantify 5000 proteins in plasma.
Obstructive sleep apnea (OSA), a disease associated with excessive sleepiness and increased cardiovascular risk, affects an estimated 1 billion people worldwide. The present study examined proteomic biomarkers indicative of presence, severity, and treatment response in OSA. Participants (n = 1391) of the Stanford Technology Analytics and Genomics in Sleep study had blood collected and completed an overnight polysomnography for scoring the apnea−hypopnea index (AHI).
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