Publications by authors named "S Korfias"

Article Synopsis
  • The pathophysiology of pediatric hydrocephalus remains unclear, and valve-based shunt systems have been the primary treatment option since the 1950s, transitioning from ventricular-atrial systems to peritoneal systems in the 1970s.
  • The review highlights the comparison of valve types and emphasizes endoscopic third ventriculostomy (ETV) as the only surgical alternative today, which offers lower infection and re-operation rates, especially for children with previous shunt failures.
  • It also identifies key predictive factors for ETV success and attempts to determine optimal treatment strategies for different patient subgroups, aiming to improve long-term outcomes for pediatric hydrocephalus patients.
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Article Synopsis
  • Severe traumatic brain injury (sTBI) is a significant health issue, leading to around 300,000 ICU admissions each year and having a 30% mortality rate, which highlights the need for improved management despite low treatment evidence.
  • The occurrence of pulmonary embolism (PE) in sTBI patients complicates treatment due to the risks associated with anticoagulating an already injured brain.
  • A literature review was conducted, analyzing recent studies on sTBI and PE, resulting in 38 relevant papers that discuss the prevalence, risk factors, diagnostic challenges, prophylaxis timing, and treatment options for PE in these patients.
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Background: Intrathecal baclofen infusing pumps are nowadays commonly implanted in patients suffering from severe, intractable spasticity with a background of multiple sclerosis. Although intrathecal baclofen therapy is considered a safe therapeutic modality, complications are unavoidable and broadly categorized as mechanical and infectious. In the instance of a pump pocket infection, a surgical explanation of the pump is often necessary to treat the infection.

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The main subject of the current review is a specific subtype of headache, which is related to shunt over-drainage and slit ventricle syndrome, in pediatric patients harboring an implanted shunt device for the management of hydrocephalus. This clinical entity, along with its impairment regarding the quality of life of the affected individuals, is generally underestimated. This is partly due to the absence of universally agreed-upon diagnostic criteria, as well as due to a misunderstanding of the interactions among the implicated pathophysiological mechanisms.

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Trigeminal neuralgia is a severe, disabling pain and its deafferentation remains a challenge for health providers. Transcranial direct current stimulation is a non-invasive stimulation technique which finds new utility in managing pain. Therefore, the introduction of alternative, non-invasive, safe, and effective methods should be considered in treating patients with trigeminal neuralgia unresponsive to conventional treatment.

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