Publications by authors named "S Koneru"
Background: Suture-loaded long hollow needles are used in arthroscopic surgery to pass or retrieve sutures and in meniscal repair surgeries. However, manual suture loading can be time-consuming and challenging, especially with finer sutures. We present a novel technique using vacuum suction to simplify and expedite suture loading in hollow needles and similar devices.
View Article and Find Full Text PDFIntroduction: Kohlschütter-Tönz (KTS) is a rare autosomal recessive, genetically heterogeneous disorder characterized by a triad of early-onset seizures, global developmental delay or regression, and amelogenesis imperfecta of both temporary and permanent teeth. To date, 66 cases have been reported in the literature, of which 44 with genetic confirmation.
Case Report: Here we report the observation of sibling pairs in a family from a small village in India who presented with nephrocalcinosis, distal renal tubular acidosis, and skeletal abnormality.
Purpose: In patients with end-stage heart failure who undergo left ventricular assist device (LVAD) implantation, higher pulmonary vascular resistance (PVR) is associated with higher right heart failure rates and ineligibility for heart transplant. Concomitant mitral regurgitation (MR) could potentially worsen pulmonary hemodynamics and lead to worse outcomes; however, its effects in this patient population have not been specifically examined.
Methods: Using an institutional database spanning November 2003 to August 2017, we retrospectively identified patients with elevated PVR who underwent LVAD implantation.
Article Synopsis
- PAMAM dendrimers, particularly the generation 4 (G4) version with a fully amine surface, are highly toxic to cells, prompting researchers to modify them for better biocompatibility by introducing neutral hydroxyl groups.
- The modified G4-90/10 dendrimers, with a surface changing to 10% amine and 90% hydroxyl, show less toxicity and effective cellular uptake in various cell types, including neurons and stem cells.
- Studies demonstrate that these dendrimers migrate within the brain after injection, with the G4 variety exhibiting more extensive movement patterns compared to G1 dendrimers, particularly in the anterior, posterior, and lateral directions, along with unique projections to cortical areas.
Article Synopsis
- The study looked at strokes caused by a neck problem called carotid artery web (CaW) in young patients, who often don't have typical stroke risk factors.
- Researchers used a score called RoPE to see how many patients had high-risk profiles related to CaW, and found that many had high scores.
- The results suggest that doctors need to look for CaW in stroke patients, even if they have a condition called patent foramen ovale (PFO), to figure out the real cause of their strokes.