Publications by authors named "S Komoly"
Article Synopsis
- Middle cerebral artery occlusion (MCAO) models exhibit significant variability in outcomes, complicating treatment evaluations and highlighting the need for early outcome predictors.
- A study involving fifty-nine male rats assessed MRI diffusion data before and after reperfusion to predict outcomes, measuring survival rates and neurological scores.
- Results showed that animals who died early had larger lesion volumes and lower diffusion metrics at reperfusion, while those who survived exhibited reduced lesion sizes and higher metrics, indicating that diffusion MRI immediately after reperfusion is more effective for predicting outcomes than measurements taken during occlusion.
Background And Purpose: Multifocal motor neuropathy (MMN) is a rare, immune-mediated illness attacking ex-clusively motor nerves. It is known that oxidative stress is present in peripheral neuropathies, but it has not been investigated MMN.
Methods: We measured in our prospective study the L-arginine, symmetric and asymmetric dimethylarginine (SDMA, ADMA) serum concentrations of 10 patients and 10 controls before and after intravenous immunoglobulin treatment (IVIG), as markers of the L-arginine/NO pathway involved in chronic inflammation and oxidative stress.
Background And Purpose: A variant of benign paroxysmal positional vertigo (BPPV) involves the subjective report of vertigo without the coinciding nystagmus. This presentation includes truncal retropulsion when sitting up from the ipsilesional provocative test (ie, Dix-Hallpike), which we term type 2 BPPV. The primary objective of this study is to prospectively determine the prevalence and describe the clinical course of type 2 BPPV.
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- A population-based study was conducted to characterize and compare clinical features of aquaporin-4 antibody positive neuromyelitis optica spectrum disorder (AQP4-Ab+ NMOSD) between Danish and Hungarian patients.
- Results showed Danes presented more with transverse myelitis and long-term spinal cord damage, while Hungarians more often exhibited optic neuritis with similar visual outcomes.
- The study highlighted significant differences in disease prevalence and incidence rates between the two populations, indicating a need for further genetic and environmental research in NMOSD.
The absence of nigral hyperintensity is a promising MR marker for Parkinson's disease (PD), but its small size imposes limitations on its routine use. Our aim was to compare Multi Echo Data Image Combination (MEDIC), segmented echo-planar imaging (EPISEG) and fluid-attenuated inversion recovery (FLAIR) sequences, as well as both magnitude (MAG) and susceptibility-weighted imaging (SWI) reconstructions of single-echo gradient echo for nigral hyperintensity imaging. Twenty-five healthy and twenty PD subjects were included.
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