Publications by authors named "S Klima Carrie"

Background: The role of objective nasal airflow measures using peak nasal inspiratory flow (PNIF) and rhinospirometry in supporting clinical examination findings when offering patients septoplasty remain undefined.

Objective: To explore the baseline relationships between clinical examination findings, subjective reported symptoms and objective nasal patency measures in nasal obstruction.

Methods: This is a sub-study of the NAIROS trial.

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The studyCarrie S, O'Hara J, Fouweather T, et al. Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial. 2023;383:e075445.

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Background: The indications for septoplasty are practice-based, rather than evidence-based. In addition, internationally accepted guidelines for the management of nasal obstruction associated with nasal septal deviation are lacking.

Objective: The objective was to determine the clinical effectiveness and cost-effectiveness of septoplasty, with or without turbinate reduction, compared with medical management, in the management of nasal obstruction associated with a deviated nasal septum.

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Article Synopsis
  • * Conducted across 27 NHS hospitals in Great Britain, the trial randomly assigned 453 participants to either undergo tonsillectomy or receive conservative care, focusing on tracking various outcomes related to sore throat symptoms.
  • * Key objectives included measuring total sore throat days over 24 months, assessing the severity and impact of episodes on daily life, and analyzing economic factors like cost per sore throat day avoided and quality-adjusted life years gained.
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