Publications by authors named "S Kleine"
Article Synopsis
- - The study aimed to determine how different sedation protocols (MVH, DH, H) affected the amount of alfaxalone needed for anesthesia in healthy Beagle dogs and to assess various cardiopulmonary metrics.
- - In this experiment, dogs premedicated with MVH required less alfaxalone for induction compared to those given DH or H and experienced a higher incidence and duration of hypotension during anesthesia.
- - The findings suggest that while MVH is effective for reducing alfaxalone dosage, it may lead to significant drops in arterial pressure, indicating a trade-off in its clinical use.
Clonazepam causes sedation and psychomotor impairment in people. Due to similarities between people and swine in response to benzodiazepines, clonazepam may represent a viable option to produce mild-to-moderate tranquillization in pigs. The objective of this study was to determine the pharmacokinetic profile of a single oral dose (0.
View Article and Find Full Text PDFObjectives: The main objective of this study was to compare the postoperative analgesic effects of grapiprant with those of robenacoxib in cats undergoing ovariohysterectomy (OVH).
Methods: In total, 37 female cats (age range 4 months-10 years, weighing ⩾2.5 kg) were enrolled in a prospective, randomized, masked, non-inferiority (NI) clinical trial.
Both pet and research pigs can suffer from some degree of pain from surgery, injuries, or osteoarthritis (OA). Despite this, there is a paucity of data on safe and effective analgesia agents in pigs. Grapiprant is an EP4 antagonist that blocks the action of the pro-inflammatory prostanoid, PGE .
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