Publications by authors named "S Kjellberg"

Article Synopsis
  • - Small airway dysfunction (SAD) is a significant aspect of pediatric asthma, and traditional spirometry may not effectively detect it; alternative methods like multiple breath washout (MBW) and oscillometry could offer better sensitivity.
  • - In a study of 57 asthmatic children aged 8-18, SAD was detected in 63% of participants using oscillometry, 54% via MBW, and 44% through spirometry, with nearly 80% showing SAD when considering both alternate methods.
  • - Findings suggest that MBW and oscillometry assess different elements of SAD and work best together; notably, MBW-derived measures correlated more closely with key clinical features than oscillometry.
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Article Synopsis
  • The study investigated small airway dysfunction (SAD) in individuals exposed to sulfur mustard (SM) compared to those unexposed, using non-invasive lung function tests.* -
  • Results showed that 14 out of 15 SM-exposed individuals had SAD, indicated by increased small airway resistance and ventilation heterogeneity, while only a few showed consistent abnormalities across different tests.* -
  • The findings suggest that SM exposure is linked to long-term respiratory issues, highlighting the importance of using both impulse oscillometry (IOS) and nitrogen multiple breath washout (NMBW) to effectively diagnose SAD.*
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Lingering breathing difficulties are common after COVID-19. However, the underlying causes remains unclear, with spirometry often being normal. We hypothesized that small airway dysfunction (SAD) can partly explain these symptoms.

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Background: Respiratory functional sequelae in COVID-19 patients admitted to the intensive care unit for invasive ventilation are sparsely reported. The aim of this study was to investigate the radiological lung appearance, lung function and their association at 6 months after hospital discharge. It was hypothesized that the degree of pathological morphology on CT scans would correlate with lung function at the time of follow-up.

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We have previously shown that functional residual capacity (FRC) and lung clearance index were significantly greater in sleeping healthy infants when measured by N (nitrogen) washout using 100% O (oxygen) versus 4% SF (sulfur hexafluoride) washout using air. Following 100% O exposure, tidal volumes decreased by over 30%, while end-expiratory lung volume (EELV, i.e.

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