Lingering breathing difficulties are common after COVID-19. However, the underlying causes remains unclear, with spirometry often being normal. We hypothesized that small airway dysfunction (SAD) can partly explain these symptoms.
View Article and Find Full Text PDFBackground: Respiratory functional sequelae in COVID-19 patients admitted to the intensive care unit for invasive ventilation are sparsely reported. The aim of this study was to investigate the radiological lung appearance, lung function and their association at 6 months after hospital discharge. It was hypothesized that the degree of pathological morphology on CT scans would correlate with lung function at the time of follow-up.
View Article and Find Full Text PDFWe have previously shown that functional residual capacity (FRC) and lung clearance index were significantly greater in sleeping healthy infants when measured by N (nitrogen) washout using 100% O (oxygen) versus 4% SF (sulfur hexafluoride) washout using air. Following 100% O exposure, tidal volumes decreased by over 30%, while end-expiratory lung volume (EELV, i.e.
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