Publications by authors named "S Kiuchi"

Introduction: We aimed to determine the impact of prior antimicrobial treatment on recurrent Clostridioides difficile infection (CDI) based on days of antibiotic spectrum coverage (DASC) and predict the risk of recurrence to guide the selection of appropriate initial therapeutic agents.

Methods: We assessed the antimicrobial treatment administered to 195 patients with a history of CDI for 28 days before testing positive for C. difficile using DASC and illness severity using ATLAS scores.

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  • The study introduces MS-DIAL 5, a software designed for analyzing complex mass spectrometry data to better understand lipid structures and localization, integrating a species-specific lipidome database for enhanced accuracy.* -
  • With optimized settings, MS-DIAL 5 accurately identified lipid structures for 96.4% of tested standards and effectively assigned specific positions in lipids, particularly for complex molecules found in the eye.* -
  • The research also identified an enzyme (glycerol 3-phosphate acyltransferase) linked to the incorporation of important fatty acids into lipids, using both mass spectrometry techniques and experimental validation.*
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  • - Lower socioeconomic status (SES) in childhood is linked to higher dental pain in older adults, irrespective of their current SES, highlighting a potential long-lasting impact of early life conditions on oral health.
  • - A study analyzed data from over 21,000 participants aged 65 and older, revealing that those with low childhood SES were more likely to suffer from dental pain in later life, with a significant portion of this association explained by current SES and the number of remaining teeth.
  • - The findings underscore the need for policies and interventions targeting childhood SES to promote better oral health outcomes as individuals age, emphasizing that early life conditions can shape dental health in later years.
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Objectives: Previous studies have reported that tooth loss is associated with an increased risk of dementia; however, few have explored the association between number of teeth and dementia-free and total life expectancies. We investigated whether having more teeth is associated with longer dementia-free and total life expectancies.

Design: A 10-year follow-up prospective cohort study from 2010 to 2020.

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Objective: The most important aspect of managing heart failure (HF) is preventing rehospitalization. Bundle branch block (BBB), particularly left BBB (LBBB), has been a known risk factor for worsening prognosis, whereas no such consideration has been made for right BBB (RBBB). However, recent research has shown that RBBB was associated with increased mortality.

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