Associations of malnutrition factors with dysphagia mediated by ADL among nursing home residents.

Objective: The potential link between malnutrition and dysphagia along with its underlying mechanisms remains unknown. This study aimed to investigate the association between malnutrition factors and dysphagia mediated by a decline in activities of daily living (ADL) among nursing home residents.

Methods: This cross-sectional study used data from 705 nursing home residents.

Virtual reality-based myoelectric prosthetic control training: Effects of action observation and motor imagery with visual feedback of electromyographic signals.

Background: Conventional myoelectric prostheses (myo-prostheses) training involves repetitive grasping and manipulation training, which requires considerable training time. It is necessary to develop a short and efficient myo-prostheses training. This study aimed to verify the immediate and sustained effects of action observation and motor imagery (AOMI) using virtual reality (VR) on myo-prostheses control and clarify the effect of visual feedback of electromyogram (EMG) signals during AOMI using VR.

Effects of ambient atmospheric pressure on intraocular pressure measured using a Goldman applanation tonometer in normal eyes under ordinary conditions.

Purpose: Little is known about the effects of ambient atmospheric pressure (AP) on intraocular pressure (IOP) under ordinary conditions. This study aimed to investigate the effects of AP on Goldmann applanation tonometer-measured IOP (GAT-IOP) in normal eyes under everyday atmospheric conditions adjusting for effects of possible confounding factors including other climatic factors.

Methods: Data obtained from 2,431 normal healthy eyes of 2,431 subjects (mean age: 56.

Loss of function in causes DNA methylation signature similar to that in Wolf-Hirschhorn syndrome.

Purpose: Wolf-Hirschhorn syndrome (WHS), a contiguous gene syndrome caused by heterozygous deletions of the distal short arm of chromosome 4 that includes , reportedly causes specific DNA methylation signatures in peripheral blood cells. However, the genomic loci responsible for these signatures have not been elucidated. The present study aims to define the loci underlying WHS-related DNA methylation signatures and explore the role of in these signatures.

Corneal Endothelial Cell Morphology in Eyes With Down Syndrome.

Purpose: To explore the morphological characteristics of corneal endothelial cells in eyes with Down syndrome.

Methods: We conducted a comparative analysis of corneal endothelial cell density, coefficient of variation, hexagonal cell appearance rate, and corneal thickness using specular microscopy. Our study included 21 eyes of 11 patients with Down syndrome and 37 eyes of 19 control subjects.