Publications by authors named "S Khongthong"
Heat stress (HS) has become a major concern for the poultry industry in many countries. HS impacts gut health by causing damaged mucosal microstructures, increased oxidative stress, weakened immunity, and heightened permeability to toxins and poultry pathogens. We investigated the potential benefits to broiler chickens subjected to HS of dietary supplementation with Bacillus subtilis 14823.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on evaluating the wound healing properties of a chitosan-based hydrogel with pyroligneous acid in diabetic mice, addressing the challenge of excessive inflammation in diabetic wounds.
- Pyroligneous acid, derived from palm kernel shell biomass, contains compounds that may enhance the healing process, as evidenced by improved wound contraction and tissue response in treated animals.
- Results showed that the hydrogel significantly accelerated healing in a dose-dependent manner, with the highest dose producing effects comparable to standard treatments, while also promoting important signaling pathways involved in tissue regeneration.
Background: Decolonisation is considered a valuable means to reduce Staphylococcus aureus infection rates. However, previous topical strategies targeting the nose or skin had little success, and oral antibiotic-based decolonisation is ill advised because of eradication of the microbiota and development of antibiotic resistance. We previously showed that the probiotic Bacillus subtilis significantly diminished S aureus at the main intestinal colonisation site via specific bacterial interaction in mice; in this study, we tested this probiotic approach to control S aureus colonisation in humans.
View Article and Find Full Text PDFPolysaccharides from the red seaweed Gracilaria fisheri possess many functions, which include antioxidant, antiviral, and antibacterial activities. However, detailed data on their immunomodulatory activities are scarce. Here, we isolated sulfated galactans (SG) from G.
View Article and Find Full Text PDFArticle Synopsis
- Probiotic Bacillus bacteria can significantly reduce colonization of the harmful pathogen Staphylococcus aureus in humans.
- The study identifies fengycins, a type of Bacillus lipopeptide, as the active component that disrupts S. aureus communication, making it less virulent.
- These findings highlight a potential probiotic approach to prevent and treat S. aureus infections by targeting bacterial signaling processes.