Diode Laser versus Conventional Surgical Circumferential Supracrestal Fiberotomy in Preventing Relapse of Orthodontically Derotated Teeth: A Randomised Control Trial.

Objective: To evaluate the effectiveness of a diode laser (810 nm) for circumferential supracrestal fiberotomy compared with conventional surgical circumferential supracrestal fiberotomy in preventing rotational relapse in orthodontically treated cases.

Methods: Seventy-six patients (age range from 18-25 years) with mandibular crowding ranging between 5-8 mm and rotation >10˚ (from the individualized arch form) treated non-extraction with a straight wire appliance (McLaughlin, Bennet, Trevisi; 0.022 inch) prescription were selected for the study.

Molecular docking and physicochemical studies of 1,3-benzodioxole tagged Dacarbazine derivatives as an anticancer agent.

Cancer, the biggest cause of death globally, remains a tough illness despite enormous advances in therapy. In the present study, 1,3-benzodioxole-tagged dacarbazine derivates were investigated as microtubule inhibitors in order to control cancer as microtubules are involved in cell proliferation. The tubulin protein was analyzed and its structure was validated by various protein validation tools.

Multi-omics and machine learning for the prevention and management of female reproductive health.

Females typically carry most of the burden of reproduction in mammals. In humans, this burden is exacerbated further, as the evolutionary advantage of a large and complex human brain came at a great cost of women's reproductive health. Pregnancy thus became a highly demanding phase in a woman's life cycle both physically and emotionally and therefore needs monitoring to assure an optimal outcome.

Comparative Evaluation of Serum High-sensitivity C-Reactive Protein and Complete Hemogram Indices in Subjects with and without Apical Periodontitis: A Prospective Interventional Study.

Introduction: This study aimed to compare the levels of high-sensitivity C-reactive protein (hsCRP) and complete hemogram (CH) parameters before and after root canal treatment in patients with apical periodontitis (AP) and healthy controls.

Methods: Twenty-five patients with asymptomatic AP in a single permanent tooth were recruited along with age- and sex-matched healthy controls. Baseline serum hsCRP and CH parameters were recorded in both groups.