Comparative evaluation of the effect of nitrofurantoin and triple antibiotic paste on the push-out bond strength of epoxy resin sealer: An study.

Context: Following chemomechanical preparation, the application of intracanal medicaments is recommended to further decrease the microbial count. To combat endodontic infections, the application of antibiotics as intracanal medicaments has been an option for years in endodontics.

Aim: The aim of this study was to compare and evaluate the effect of antibiotic pastes on the push-out bond strength (POBS) of resin-based root canal sealer.

Role of lung ultrasound score in early prediction of bronchopulmonary dysplasia in preterm neonates.

Background: The use of lung ultrasound score (LUS) to predict bronchopulmonary dysplasia (BPD) is still evolving. While LUS is widely available and accurate, there is limited evidence from low- and middle-income countries. We aim to assess LUS's predictive ability for BPD in preterm neonates less than 30 weeks gestation.

Paving the way toward treatment solutions for CTNNB1 syndrome: a patient organization perspective.

The CTNNB1 Connect & Cure and CTNNB1 Foundation, alongside Asociación CTNNB1, CTNNB1 Italia, Association CTNNB1 France, and researchers and clinicians globally are dedicated to finding effective treatments and cures for CTNNB1 syndrome. The syndrome is also characterized by progressive spasticity, which can in some cases cause loss of already achieved motor milestones. Since 2019, they have brought together researchers from different fields and invested in various research efforts to advance the search for treatment solutions for patients with CTNNB1 syndrome.

Complement activation as a biomarker for platelet-activating antibodies in heparin-induced thrombocytopenia.

Background: Immunoglobulin G antibodies (Abs) to platelet factor 4 (PF4) complexed to heparin (PF4/H) commonly occur after H exposure but cause life-threatening complications of H-induced thrombocytopenia (HIT) in only a few patients. Presently, only platelet activation assays reliably distinguish anti-PF4/H Abs that cause disease (HIT Abs) from those likely to be asymptomatic (AAbs).

Objectives: Recent studies indicate that complement activation is an important serologic property of HIT Abs and is essential for IgG Fc receptor IIA-mediated cellular activation.

Macrodystrophia lipomatosa: Clinical and radiological insights into localized gigantism.

A rare type of localized gigantism known as macrodystrophia lipomatosa is characterized by a disproportionate increase in fibroadipose tissues and a gradual overgrowth of all mesenchymal elements. The distribution in the lower extremities' plantar nerves and the upper extremity's median nerve is most commonly observed. This abnormality is congenital and typically manifests at birth or during the neonatal stage.