Association of Lung Fibrotic Changes and Cardiological Dysfunction with Comorbidities in Long COVID-19 Cohort.

. Long COVID-19 symptoms appeared in many COVID-19 survivors. However, the prevalence and symptoms associated with long COVID-19 and its comorbidities have not been established.

[An experimental model of pulmonary aspergillosis].

The model of experimental chronic pulmonary aspergillosis has been obtained in mice and guinea pigs by the intrapulmonary infection of the animals with the suspension of Aspergillus mycelium and spores in complete Freund's adjuvant. Such method of infection has made it possible to produce chronic local mycotic process. Morphologically, focal inflammatory changes of the lung tissue with the subsequent formation of a multitude of small abscesses in these areas have been observed as characteristic manifestations of aspergillosis.

[Ultrastructure of the intercalary disks in cardiac muscle tissue of permanent and temporary residents at high altitudes].

In animals temporary adapted to the Alpine conditions, the intermembranous space of the intercalated disc is dilated 3-5 and more times, while in permanent inhabitants of the Alpine regions similar dilatation is not observed. Probably, in the latters numerous intercalated discs increase adhesive force of cardiomyocytes, extent of zones with low electrical resistance and increase contraction of myofibrills, thus promoting transmission of excitation from cell to cell.