Clinical Outcomes and Complications of Total Knee Arthroplasty with Posterior-Stabilized and Cruciate-Retaining Prostheses in Osteoarthritis Patients with Valgus Deformity.

Aim: This study aimed to evaluate the short- and long-term outcomes and complications of total knee arthroplasty (TKA) using posterior-stabilized (PS) and cruciate-retaining (CR) prosthesis in patients with osteoarthritis (OA) and valgus knee deformity.

Methods: A retrospective analysis was conducted on 200 patients with OA and valgus knee deformity who underwent TKA between February 2021 and November 2023. The cohort was divided into the PS group (n = 108) and the CR group (n = 92).

Expandable konjac fiber modulates appetite and chyme digestion in vivo by stomach-intestine-brain axis.

Appetite regulation is a lifestyle intervention strategy to maintain health. The regulatory effects of dietary fiber (especially insoluble dietary fiber), as a crucial element of the nutritional composition, on appetite remain poorly understood. This study investigated modulatory effects of konjac fiber (KF, with high and low expansion) and konjac powder (KP) on chyme digestion, gastrointestinal hormones, intestinal microbiota, appetite genes in hypothalamus, GLP-1 receptor (GLP-1R) protein in various tissues of rats by dietary intervention.

Core-shell structured waste paper/biocarbon composite providing exceptional electromagnetic interference shielding and flame retardancy.

The widespread use of electronic devices significantly facilitates daily human life, but also leads to increasingly serious electromagnetic pollution. Therefore, it is necessary to develop eco-friendly electromagnetic interference (EMI) shielding materials with excellent overall performance. Here, we prepare a waste paper/biocarbon (WP/BC) composite with a distinct densely self-bonded core-shell structure through the partial dissolution co-mixing process.

Single-cell and spatial transcriptomics analysis reveals that Pros1 oligodendrocytes are involved in endogenous neuroprotection after brainstem stroke.

Background: Brainstem stroke accounts only 7-10 % of all ischemic stroke while it had more morbidity and mortality. As the predominant cellular component of nerve tracts, oligodendrocytes might provide some neuroprotection against ischemic injury in the context of brainstem stroke, but the underlying mechanism remains unclear.

Method: A mouse model of brainstem stroke was established, and single-cell RNA sequencing and spatial transcriptomic sequencing analysis were performed to elucidate the phenotype of oligodendrocytes within this context.