Publications by authors named "S Kawada"
Background: Atrial tachyarrhythmias (ATAs) are the primary cause of inappropriate implantable cardioverter-defibrillator (ICD) therapy in patients with idiopathic ventricular fibrillation (IVF) and are associated with decreased quality of life and increased mortality. Nonetheless, the incidence of ATAs in IVF cases has not been clarified.
Objective: The study sought to determine the incidence and clinical significance of ATAs in patients with IVF compared with those with Brugada syndrome (BrS).
Article Synopsis
- Rastelli surgery is performed to correct congenital heart defects, but late-onset cardiac arrhythmias are a notable complication, and there's limited data on their occurrence after this surgery.
- In a study of 55 patients followed for over 24 years, 38.4% experienced tachyarrhythmias, with older age at surgery linked to a higher risk; 21.8% had bradyarrhythmias, and some required catheter ablation.
- The results indicate that arrhythmia prevalence is significant and increases with age post-surgery, emphasizing the need for long-term monitoring in patients who underwent Rastelli surgery.
Article Synopsis
- * Neoself-antigens, which are unusual self-targets, are presented on MHC-II when the invariant chain is absent, leading to the activation of autoreactive T cells in SLE.
- * Research shows that these neoself-reactive T cells expand in SLE patients and can be activated by cells reactivated by the Epstein-Barr virus, indicating a significant relationship between viral infections and the development of lupus.