Publications by authors named "S Katyayani"
Myasthenia gravis (MG) is an autoimmune disorder caused by antibody-mediated attack against skeletal muscle nicotinic acetylcholine receptor (AchR) at neuromuscular junction. A close relationship exists between heat shock proteins (HSPs) and numerous autoimmune diseases. HSPs are over expressed to protect the host against various insults.
View Article and Find Full Text PDFSignificance of antibody detection in the diagnosis of cryptococcal meningitis.
J Immunoassay Immunochem
October 2012
Article Synopsis
- Cryptococcus neoformans causes Cryptococcosis, a serious infection mostly affecting AIDS patients, with sonicated proteins showing potential antigenic properties.
- The study involves preparing antigens from cryptococcal culture and using ELISA to identify antibodies in cerebrospinal fluid (CSF) samples from cryptococcal meningitis cases.
- Results suggest that antibody detection is valuable for early diagnosis, particularly when combined with traditional methods like India ink staining, offering high sensitivity (83%) and specificity (100%) for diagnosing cryptococcal infections.