Publications by authors named "S Kasuga"
Background/aim: The efficacy of preoperative chemoradiotherapy (CRT) in lower rectal cancer is determined by its effects on the primary tumor. However, the effects on the mesorectum have not been investigated. Furthermore, edema in the dissection planes is frequently observed after postoperative CRT.
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- The study focuses on analyzing the polyphenol content, specifically free flavonoids, in the bran of a new red sorghum variety (RILN-156) compared to other commercial varieties, using a process that removes the bran.
- Various methods, including colorimetric techniques and advanced metabolomics (LC/MS and CE/MS), were used to quantify different polyphenolic components and identify 19 flavonoids, with galangin and daidzein being the most abundant.
- The results indicated that RILN-156 has a higher concentration of polyphenolic content and antioxidant capacity than the other varieties, suggesting its potential for industrial use and further health-related research.
Fusicoccin-A (FC-A) is a diterpene glucoside produced by a pathogenic fungus. Since its discovery, FC-A has been widely recognized as a phytotoxin that induces stomatal opening and leaf wilting, eventually leading to plant death. In this study, we present the first evidence that FC-A enhances plant growth by stabilizing the protein-protein interaction between plasma membrane (PM) H-ATPase and 14-3-3 in guard cells.
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- The study introduces robust design methods for a vertical avalanche photodiode-based CMOS image sensor, focusing on three practical factors: eliminating guard rings for better pixel isolation, ensuring device performance is stable regardless of voltage and temperature changes, and maintaining consistent operation under intense light conditions.
- The design minimizes trade-offs between electric field concentration and pixel isolation, validated through both simulations and experiments, resulting in effective optimization strategies.
- A global feedback resistor is used to stabilize device characteristics, while an in-pixel overflow transistor improves resistance to high illumination; the sensor's robustness is confirmed by extensive testing on multiple chips under extreme conditions for over 1000 hours.
Purpose: Pteridines are metabolites of tetrahydrobiopterin (BH), being coenzymes for nitric oxide synthase (NOS). No study has clarified the relationship among pteridines and NOS, fractional exhaled nitric oxide (FeNO) generated by pteridines, and reactive oxygen species. In this study, we administered arginine, a precursor of NO, and confirmed changes in the levels of pteridines, FeNO, and reactive oxygen species and their relationship to clarify the pathogenesis of airway inflammation in which oxidative stress is involved, such as bronchial asthma.
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