Publications by authors named "S Kastl"
Article Synopsis
- Preeclampsia (PE) is linked to reduced blood flow to the placenta, which can cause heart function changes in pregnant women; this study investigates these cardiac characteristics and their relationship with NT-proBNP levels.
- A retrospective analysis of 65 PE-diagnosed pregnant women was conducted using echocardiography, revealing normal left ventricular size and function, but impaired longitudinal contractility and borderline left atrial size.
- Increased NT-proBNP levels were associated with lower gestational age at delivery and were indicative of maternal cardiac changes, with a high preterm birth rate due to worsening PE or fetal health issues linked to placental insufficiency.
Background: Patent foramen ovale (PFO) closure is recommended for secondary prevention of cryptogenic stroke. However, data on long-term results are limited. We aimed to evaluate safety and efficacy of transcatheter PFO closure and predict neurologic recurrence.
View Article and Find Full Text PDFThe incidence of atrial fibrillation (AF) in patients with heart failure with preserved ejection fraction (HFpEF) is high. Impaired left atrial (LA) function is a major determinant in HFpEF. However, the extent of electrical LA tissue degeneration in HFpEF is unknown.
View Article and Find Full Text PDFCardiac magnetic resonance (CMR) studies reported CMR abnormalities in patients with mild-moderate SARS-CoV-2 infection, suggesting ongoing myocardial inflammation. Patients ( = 278, 43 ± 13 years, 70.5% female) with post-acute sequelae of SARS-CoV-2 cardiovascular syndrome (PASC-CVS) were included prospectively into the Vienna POSTCOV Registry between March 2021 and March 2023 (clinicaltrials.
View Article and Find Full Text PDFBackground: CILP-1 regulates myocardial fibrotic response and remodeling and was reported to indicate right ventricular dysfunction (RVD) in pulmonary hypertension (PH) and heart failure (HF). This study examines CILP-1 as a potential biomarker for RVD and prognosis in heart failure with reduced ejection fraction (HFrEF) patients on guideline-directed medical therapy.
Methods: CILP-1 levels were measured in 610 HFrEF patients from a prospective registry with biobanking (2016-2022).