Publications by authors named "S Kassab"

Background: Sociocultural competence is essential for health professions education (HPE) students. However, the relationships between university campus environment, sense of belonging, and sociocultural engagement of HPE students remain unclear. We hypothesized that a university environment promoting students' participation in social activities enhances their sociocultural engagement, which is mediated through the students' sense of belonging, ultimately increasing their satisfaction with university experience.

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Background: This research explores the relationships between the educational environment, student engagement, and academic achievement in Health Professions Education (HPE) , specifically examining the mediating role of engagement.

Methods: The study used cross-sectional design, and data were collected from 554 HPE students via self-report questionnaires. The Dundee Ready Education Environment Measure (DREEM) assessed the educational environment while the University Student Engagement Inventory measured learning engagement across the behavioral, emotional, and cognitive dimensions.

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Article Synopsis
  • Proteolysis Targeting Chimeras (PROTACs) are innovative tools in targeted protein degradation (TPD) that hold promise for drug development, but predicting their effectiveness is challenging.
  • This study introduces an AI-powered PROTAC Activity Prediction Tool (AI-DPAPT) that leverages machine learning and molecular fingerprinting techniques to accurately predict PROTAC activity based on chemical structures.
  • The research demonstrated strong performance across various machine learning classifiers, with the Random Forest model yielding an impressive area under the curve score of 0.97, enhancing the understanding of structure-activity relationships in TPD and potentially accelerating drug development processes.
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Purpose: To develop and assess three-dimensional models of physeal fractures in dog femurs (3D MPFDF) using radiographic imaging.

Methods: The study was conducted in three phases: development of 3D MPFDF; radiographic examination of the 3D MPFDF; and comparative analysis of the anatomical and radiographic features of the 3D MPFDF.

Results: The base model and the 3D MPFDF achieved high fidelity in replicating the bone structures, accurately maintaining the morphological characteristics and dimensions such as length, width, and thickness, closely resembling natural bone.

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Introduction: Behçet disease (BD) is an inflammatory multisystem disorder of unknown etiology, believed to be triggered by infection and environmental factors in genetically predisposed individuals. The significance of understanding BD lies in its impact on global health due to its diverse clinical manifestations and geographical distribution.

Areas Covered: This review discusses the epidemiology of BD, emphasizing its prevalence estimated at 10.

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